"500.15 - Direct requests for Global.asax are not allowed" is only supported by Microsoft IIS (Internet Information Services) web servers.
Global.asax = This is a file in the root of the IIS web site that contains scripts of things to do when the site comes up, and when a web user connects and disconnects to the server. It is a target for hackers, so access is highly restricted for site security.
The five hundred series of errors indicate something is wrong at the server and it is unable to complete the action.
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